Definition

Koob & Le Moal

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Koob & Le Moal — repeated drug administration shifts the hedonic set-point downward ↗

Supporting facts

allostasis is a McLuhanian mechanism ↗
The paper bridges McLuhan media theory, ADHD/inner-speech/affect-labeling neuroscience, the Koob–allostasis addiction model, and the extended-mind / enactivist / PSM frameworks. ↗